@thesis{thesis,
		author={Posut  Moan Anjelus},
		title ={Tingkat kesembuhan luka terbuka pada tikus putih (Rattus norvegicus) yang diberi salep daun kirinyuh (chromolaena odorata L)},
		year={2021},
		url={http://erepository.uwks.ac.id/10305/},
		abstract={TINGKAT KESEMBUHAN LUKA TERBUKA PADA TIKUS 
PUTIH (Rattus norvegicus) YANG DIBERI SALEP DAUN 
KIRINYUH (chromolaena odorata)
Anjelus Moan posut
ABSTRACT 
The purpose of this study was to determine the rate of open wound healing 
based on the size of the wound diameter shrinkage in white rats (Rattus norvegicus) 
given the ointment of kirinyuh leaf extract (Chromolaena odorata) and to determine 
the appropriate concentration of kirinyuh leaf extract (Chromolaena Odorata) for 
healing open wounds in rats. white (Rattus norvegicus). This type of research is 
experimental with a completely randomized design (CRD). The sample used was 1 
kg of kirinyuh leaves (Chromolaena odorata) obtained from Maumere NTT, 25 
white rats (Rattus norvegicus) which were divided into 5 treatment groups and 5 
replications. P0(-) is a negative control: 5 white rats (Rattus norvegicus) given 
aquadest. P4(+) is a positive control: 5 white rats (Rattus norvegicus) given 
bioplacenton ointment. P1 : 5 white rats (Rattus norvegicus) given 5% kirinyuh leaf 
extract ointment (Chromolaena odorata). P2 : 5 white rats (Rattus norvegicus) given 
10% kirinyuh leaf extract ointment (Chromolaena odorata). P3 : 5 white rats (Rattus 
norvegicus) given 15% kirinyuh leaf extract ointment. The results showed a very 
significant difference between groups (P2) compared to groups (P1, P3, P4 and P0) 
(P<0.01). Based on the results of the study, it can be concluded that the leaf extract 
of kirinyuh (Chromolaena odorata) can be used as a ointment against white rats 
(Rattus norvegicus).
Keywords: kirinyuh leaf ointment, open wound, Chromolaena odorata., Rattus 
norvegicus}
		}