@thesis{thesis,
		author={Muhammad  Dienulloh Qasyfur Rohman},
		title ={OPTIMASI HPMC DAN KARBOPOL DALAM FORMULASI SEDIAAN
GEL ANTISEPTIK EKSTRAK ETANOL DAUN BELUNTAS
(Pluchea indica L.) DAN AKTIVITAS ANTIBAKTERI
TERHADAP Staphylococcus aureus},
		year={2020},
		url={http://librepo.stikesnas.ac.id/195/},
		abstract={Beluntas leaf (Pluchea indica, L.) is one of the plants that has potential as
an antibacterial, Where the leaves of Beluntas have several compounds, one of
these is a flavonoid which has antibacterial activity. The aim of this research is to
determine the optimum composition of HPMC and carbopol which will be
formulated in the preparation of antiseptic gel ethanol extract of beluntas leaf
using the simplex lattice design method. The extraction method used in this study
is maseration with ethanol as a solvent. Antiseptic gel manufacturing is done by
optimizing the base of HPMC and Carbopol. Then testing the quality of the gel
preparation and the results obtained that meet the requirements of the
homogeneity, pH, dispersion, viscosity, consistency and stability test of the gel
preparation. The optimum formula of antiseptic gel based on the simplex lattice
design method is on a combination of a 4.5% HPMC base and a 0.5% carbopol.
Antibacterial activity test found inhibition zone, this shows that the antiseptic gel
preparation of the ethanol extract of beluntas leaves has the ability to inhibit
against Staphylococcus aureus bacteria with an average diameter of the zone of
inhibition by 17,66 mm.}
		}