@thesis{thesis,
		author={Ema  Rochayani Damairia},
		title ={EFEK PEMBERIAN SEDUHAN TEH HITAM (Camellia sinensis L)
DAN COKELAT (Theobroma cacao L) TERHADAP GAMBARAN
HISTOPATOLOGIS HEPAR TIKUS PUTIH (Rattus norvegicus)},
		year={2021},
		url={http://librepo.stikesnas.ac.id/757/},
		abstract={Black tea is a member of the Theaceae family which has many benefits and contains
higher caffeine than green tea. Chocolate is a commodity that generates foreign
exchange for the country and is the main ingredient for making chocolate which also
contains caffeine. Caffeine damages the liver by inhibiting the growth of connective
tissue in liver cells. The purpose of this study was to determine the histopathological
effect on the liver organs of white rats given black and chocolate tea steeping and the
damage that occurs when given in a predetermined dose and time. This research is
experimental, with 7 treatment groups. Liver organs were observed macroscopically
and microscopically. The results of macroscopic observations there were no
differences in the control and treatment groups. The results of microscopic
observations in the black tea steeping group 3 and 6 mg/200 g/day, and chocolate
steeping 3, 6, and 12 mg/200 g/day there was degeneration, black tea steeped 12
mg/200 g/day there was necrosis. The results of the Mann Whitney test showed a
significant difference in the black tea steeping group at the three doses and 12 mg/200
gr/day chocolate steeping, while 3 and 6 mg/200gr/day chocolate steeping did not
show a significant difference. It can be concluded that the administration of 3 and 6
mg/200 g/day steeping black tea and 3, 6, and 12 mg/200 g/day steeping black tea
causes degeneration and 12 mg/200 g/day black tea steeping causes necrosis.}
		}