@thesis{thesis,
		author={Anggit  Dian Aprilia},
		title ={UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL, FRAKSI NHEKSANA, ETIL ASETAT, DAN AIR DAUN BIT (Beta vulgaris L.)
TERHADAP BAKTERI Methicillin Resistant Staphylococcus aureus (MRSA)},
		year={2021},
		url={http://librepo.stikesnas.ac.id/780/},
		abstract={Methicillin Resistant Staphylococcus aureus (MRSA) is one of the
resistant strains of Staphylococcus aureus bacteria that are resistant to antibiotics
such as methicillin, penicillin, cotrimoxazole, rifampin, chloramphenicol and
gentamicin. MRSA resistance to beta-lactam antibiotics is due to changes in
penicillin-binding protein 2a (PBP2a). Based on this information, it is necessary
to find alternative medicine by utilizing active compounds in plants, namely beet
leaves.
Beet leaves were extracted using the maceration method with 96% ethanol,
then the extract was fractionated using n-hexane, ethyl acetate and water as
solvents. The resulting extracts and fractions were then tested for antibacterial
using the disc diffusion method with concentrations of 1000ppm, 500ppm,
250ppm, 125ppm, and 62.5ppm against MRSA bacteria. The diameter of the
inhibition zone obtained was then analyzed descriptively with CLSI 2020.
Ethanol extract and ethyl acetate fraction had antibacterial activity at
concentrations of 1000ppm, 500ppm, 250ppm, 125ppm, and 62.5ppm with an
average range of inhibition zone 15.06 mm-7.26 mm. The water fraction had
antibacterial activity at concentrations of 1000ppm, 500ppm, 250ppm, and 125
ppm with an average inhibition zone of 11.40 mm-6.90 mm, while at a
concentration of 62.5 ppm it did not show any antibacterial activity. N-hexane
fraction did not show any antibacterial activity, The results of the comparison with
the positive control, namely ciprofloxacin according to the CLSI, between the
extract and the fraction of beetroot leaf extract had an activity that was not
equivalent to the positive control ciprofoxacin which has a zone inhibition 17,4
mm.}
		}