@thesis{thesis,
		author={Liyona  Genta Endrati},
		title ={FORMULASI GEL EKSTRAK ETANOL DAUN SALAM (Syzygium
polyanthum (Wight) Walp) DAN UJI AKTIVITAS ANTIINFLAMASI PADA
TIKUS PUTIH JANTAN GALUR WISTAR},
		year={2021},
		url={http://librepo.stikesnas.ac.id/807/},
		abstract={Inflammation is a local reaction mechanism in the tissue to an infection or injury
by involving more mediators. Bay leaves (Syzygium polyanthum (Wight) Walp)
contains flavonoid compounds using as anti-inflammatory. Topical preparations were
chosen because they minimize unwanted side effects. This study aims to determine the
ethanol extract can be formulated in the form of a gel, compared anti-inflammatory gel
activity and physical stability of the gel.
Bay leaves were extracted by merasi method using 70% ethanol as solvent. The
ethanolic extract of bay leaves was formulated in gel preparations with concentrations
of 1.5%, 2.5%, 4%. The base and the three formulas were tested for accelerated
stability for 3 cycles at a temperature of 4?C and 40?C, the tests included organoleptic,
homogeneity, spreadability, adhesion, pH, viscosity. Anti-inflammatory test by
measuring the volume of the rat's paws. The results of the data obtained were analyzed
statistically One Way Anova.
The results of the anti-inflammatory test of the ethanol extract of the bay leaves
showed that the three concentrations had anti-inflammatory properties on the volume
of the soles induced by carrageenan. %PI produced for each concentration was
27.96%±3.70 (1.5%), 23.27%±5.62 (2.5%), 20.81%±2.02 (4%). One Way Anova
statistical results p > 0.05 where there was no significant difference between Formula
1, 2 and 3. The statistical results of One Way Anova dispersion showed that there was
no significant difference between the Basis and the three Formulas (p > 0.05). And the
statistical results of One Way Anova stickiness p < 0.05 where there is a significant
difference.}
		}