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ANALISIS CEMARAN BAHAN KIMIA OBAT DEKSAMETASON DALAM JAMU PEGAL LINU MENGGUNAKAN METODE KROMATOGRAFI LAPIS TIPIS (KLT) - DENSITOMETRI
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Institusion
Universitas Duta Bangsa
Author
KURNIASRI, NOVITA
Subject
R Medicine (General) 
Datestamp
2022-07-16 03:02:53 
Abstract :
ABSTRACT ANALYSIS OF CHEMICAL DRUG DEXAMETHASONE CONCENTRATION IN RHEUMATIC PAIN HERBAL MEDICINE USING THIN LAYER CHROMATOGRAPHY (TLC) ? DENSITOMETRIC METHOD Novita Kurniasri Medicinal chemicals are chemical substances that are used as the main ingredients of chemical drugs which are usually added to herbal preparations to strengthen the indication of the traditional medicine. Medicinal chemicals are prohibited from being added to traditional medicinal preparations. But in reality, a lot of medicinal herbs could have contain medicinal chemicals on the market sale. This purpose of this research were to know the chemical ingredients of the drug dexamethasone and the concentration contained in the rheumatic pain herbal. On the research to identify dexamethasone in reumathic pain herbal a sample code is S1, S2, and S3. The analysis of qualitative method are organoleptic test, FTIR characteristic test, TLC test, and TLC-Densitimetric test. The analysis of quantitative to know the concentration contained on the rheumatic pain herbal with TLC-Densitometric method. The result of the rheumathic pain herbal were the contaminated by dexamethasone drug. Organoleptic test to know color, smell, and taste. On FTIR test is functional groups contained in the rheumatic pain herbal sample, the functional groups of the sample code S1, S2, and S3 were compared to dexamethasone standard. The identify of TLC method to obtain Rf value dexamethasone standard and stain color is fluorescence purple on the UV 254 nm. The analysis dexamethasone concentration in TLC-Densitometric method. The results showed the presence of dexamethasone in the sample for rheumatic pain herbal. The results of the quantitative TLC-Densitometric method obtained dexamethasone concentration in rheumatic pain herbal of sample code S1, S2, S3 were 1014,64 ?g/g ; 131,15 ?g/g ; 135,54 ?g/g respectively. 
Institution Info

Universitas Duta Bangsa