UJI AKTIVITAS ANTIBAKTERI EMULGEL KOMBINASI CITRONELLA OIL 1% dan
TEA TREE OIL 5% dengan GELLING AGENT CARBOMER
(Terhadap Bakteri Propionibacterium acnes secara In Vitro)
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Institusion
Universitas Muhammadiyah Malang
Author
Subject
R Medicine (General)
Datestamp
2019-08-16 04:13:33
Abstract :
Background : The use of Citronella Oil (Cymbopogon nardus L.) and Tea Tree Oil (Melaleuca alternifoila L.) as anti-acne, because they have great antibacterial activity against Propionibacterium acnes. Goal: To determine the effect from the variations of Carbomer’s levels at 0.5%, 0.75% and 1% on the emulgel containing a combination of Citronella Oil 1% and Tea Tree Oil 5% against the Proponibacterium acnes’s inhibition. Method: Three emulgel formulas were made and replicated 3 times. Followed by Hole plate method, to test the antibacterial effectivity. Result: The average diameter of bacterial inhibition zone from the combinated emulgel for Formula 1 is 13.52 mm; Formula 2 is 12.57 mm and Formula 3 is 11.15 mm. The preparation has a strong bacterial inhibition. Conclusion: The variation of Carbomer’s level at 0.5%, 0.75% and 1% gave an effect to emulgel containing a combination of Citronella Oil and Tea Tree Oil, there was a decrease in the diameter of the bacterial inhibition zone. So, in this study there were significant differences.
Background : The use of Citronella Oil (Cymbopogon nardus L.) and Tea Tree Oil (Melaleuca alternifoila L.) as anti-acne, because they have great antibacterial activity against Propionibacterium acnes. Goal: To determine the effect from the variations of Carbomer’s levels at 0.5%, 0.75% and 1% on the emulgel containing a combination of Citronella Oil 1% and Tea Tree Oil 5% against the Proponibacterium acnes’s inhibition. Method: Three emulgel formulas were made and replicated 3 times. Followed by Hole plate method, to test the antibacterial effectivity. Result: The average diameter of bacterial inhibition zone from the combinated emulgel for Formula 1 is 13.52 mm; Formula 2 is 12.57 mm and Formula 3 is 11.15 mm. The preparation has a strong bacterial inhibition. Conclusion: The variation of Carbomer’s level at 0.5%, 0.75% and 1% gave an effect to emulgel containing a combination of Citronella Oil and Tea Tree Oil, there was a decrease in the diameter of the bacterial inhibition zone. So, in this study there were significant differences.
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