UJI AKTIVITAS ANTI JAMUR DAUN BELUNTAS (Pluchea indica)
TERHADAP JAMUR Candida albicans PENYEBAB KANDIDIASIS
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Institusion
Universitas Pakuan
Author
Riyanti, Putri
Ismanto
Komala, Oom
Ismanto
Komala, Oom
Subject
Biologi
Datestamp
2022-09-03 16:21:33
Abstract :
ABSTRACT One of the native plants of Indonesia that is widely distributed in several regions in Indonesia and has the potential to be develoved is the Beluntas plant (Pluchea indica L). Which is a plant from the Asteraceae tribe which contains alkaloids, flavonoids, tannins, essential oils, chlorogenic acid, sodium, potassium, magnesium and phosphorus while the roots contain flavonoids and tannins. Candida albicans is the most pathogenic species that attacks the skin surface, oral and vagina mucosa. Candidiasis is a problem for many suffers because of the symptoms caused by the yeast infection Candida albicans. Many people have tried to treat or eliminate candidiasis, namely by using antibiotics clearly has side affects, and the use of natural ingredients is the solution. One of them is Pluchea indica which contains flavonoids, tannins and saponins which have the potential as antifungals. The purpose of this study was to determine the concentation of Pluchea indica extract with 96% ethanol solvent which has optimal activity in inhibiting the growth of Candida albicans based on the minimum inhibitory concentration (MIC) and the width of the inhibition area (LDH). Qualitatifve phytochemical test were carried out on alkaloids, flavonoids, tannins, saponins and steroids. This anti fungal test uses the disc diffusion method. The minimum inhibitory concentration (MIC) test of Pluchea indica extract was carried out using the dilution method at concentrations of 0.625%, 1.25%, 2.5% and 5 % and the widw area of inhibition (LDH) was tested using the disc diffusion method at concentations of 5%, 10% and 20%. Keywords: Beluntas leave, Candida albicans
ABSTRACT One of the native plants of Indonesia that is widely distributed in several regions in Indonesia and has the potential to be develoved is the Beluntas plant (Pluchea indica L). Which is a plant from the Asteraceae tribe which contains alkaloids, flavonoids, tannins, essential oils, chlorogenic acid, sodium, potassium, magnesium and phosphorus while the roots contain flavonoids and tannins. Candida albicans is the most pathogenic species that attacks the skin surface, oral and vagina mucosa. Candidiasis is a problem for many suffers because of the symptoms caused by the yeast infection Candida albicans. Many people have tried to treat or eliminate candidiasis, namely by using antibiotics clearly has side affects, and the use of natural ingredients is the solution. One of them is Pluchea indica which contains flavonoids, tannins and saponins which have the potential as antifungals. The purpose of this study was to determine the concentation of Pluchea indica extract with 96% ethanol solvent which has optimal activity in inhibiting the growth of Candida albicans based on the minimum inhibitory concentration (MIC) and the width of the inhibition area (LDH). Qualitatifve phytochemical test were carried out on alkaloids, flavonoids, tannins, saponins and steroids. This anti fungal test uses the disc diffusion method. The minimum inhibitory concentration (MIC) test of Pluchea indica extract was carried out using the dilution method at concentrations of 0.625%, 1.25%, 2.5% and 5 % and the widw area of inhibition (LDH) was tested using the disc diffusion method at concentations of 5%, 10% and 20%. Keywords: Beluntas leave, Candida albicans
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