Institusion
Universitas Wijaya Kusuma Surabaya
Author
Wiargita, I Made Pratista
Subject
R Medicine (General)
Datestamp
2021-01-19 06:39:51
Abstract :
Staphylococcus epidermidis and Salmonella typhi are types of bacteria that can cause infectious diseases. Staphylococcus epidermidis infection can cause diseases such as acne, folliculitis, UTI (urinary tract infection), bullous impetigo, and furunculosis. Salmonella typhi is a gram negative bacteria that causes typhoid fever, with clinical symptoms such as fever, bacteremia and damage the organs such as the intestines and liver. According to research there are active compounds inside the onion skin, such as flavonoids, tannins, and saponins that can use as an antibacterial agent. For this reason, to the purpose of this study was to determinded the effect of red onion skin (Allium cepa L.) extract on the diameter of inhibition zone of Staphylococcus epidermidis and Salmonella typhi. This research used a laboratory experimental study, and was conducted with a post-test only control group design. This study used 30 samples each consisting of 15 samples of Staphylococcus epidermidis and 15 samples of Salmonella typhi which were divided into 3 treatment groups (consentrastion of 60%, 65%, and 70%), and 2 control groups (negative and positive) on Staphylococcus epidermidis and Salmonella typhi, receptively. The methods used to test antibacterial test is diffusion method. Result of this study showed that mean of the inhibition sone to Staphylococcus epidermidis on concentration 60% was 9 mm; 65% was 19.33 mm and concentration 70% was 11 mm. Based on the Kruskal-Wallis test, it was found that there was an effect of giving onion skin extract on Staphylococcus epidermidis, indicated by the formation of an inhibition zone at K1 (60%) 9 mm, K2 (65%) 10.33 mm and K3 (70%) 11 mm. However, giving onion skin extract (Allium cepa L.) has no effect on the inhibition zone for Salmonella typhi.