Pengaruh xanthone terhadap daya hambat bakteri salmonella thypi
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Institusion
Universitas Wijaya Kusuma Surabaya
Author
Krsna, Komang Vedanta Rama
Subject
R Medicine (General)
Datestamp
2021-01-28 01:35:49
Abstract :
Typhoid fever is a systemic infection disease and included in foodborne disease. This disease is also known as a Typhus abdominalis, Typhoid fever, and Enteric fever. The cause of typhoid fever is a pathogenic bacterium known as Salmonella typhi that leads to a systemic disease with fever, bacteremia, and inflammation that in the end causes bowel and liver damages. Xanthone is an active compound that very useful as an antiinflammation, antiallergic, antitumor, antibacterial, antivirus, and antifungal. The goal of this study is to determine the effect of xanthone on the diameter of inhibition of S. thypii. This study was conducted as an experimental laboratory with posttest only control group as it?s designed. S. thypii was used as populations on this study, and 20 Mueller-Hinton agar which divided into 5 groups with disc diffusion as the method was the amount of sample collected. The study showed that in the negative control group (K-) using the 10% of dimethyl sulfoxide solution there is no inhibition zone can be found, which means there is no diameter on the disc, and the same thing happens in the group of treatment, the results are 0mm, 0mm, 0mm, and 0mm on the B1, B2, B3, and B4 group of treatment respectively. These results conclude that the growth of S. typhii cannot be inhibited by Xanthone.
Typhoid fever is a systemic infection disease and included in foodborne disease. This disease is also known as a Typhus abdominalis, Typhoid fever, and Enteric fever. The cause of typhoid fever is a pathogenic bacterium known as Salmonella typhi that leads to a systemic disease with fever, bacteremia, and inflammation that in the end causes bowel and liver damages. Xanthone is an active compound that very useful as an antiinflammation, antiallergic, antitumor, antibacterial, antivirus, and antifungal. The goal of this study is to determine the effect of xanthone on the diameter of inhibition of S. thypii. This study was conducted as an experimental laboratory with posttest only control group as it?s designed. S. thypii was used as populations on this study, and 20 Mueller-Hinton agar which divided into 5 groups with disc diffusion as the method was the amount of sample collected. The study showed that in the negative control group (K-) using the 10% of dimethyl sulfoxide solution there is no inhibition zone can be found, which means there is no diameter on the disc, and the same thing happens in the group of treatment, the results are 0mm, 0mm, 0mm, and 0mm on the B1, B2, B3, and B4 group of treatment respectively. These results conclude that the growth of S. typhii cannot be inhibited by Xanthone.
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