Abstract :
Salmonella typhi is a bacteria that causes typhoid fever which is an acute endemic
disease that occurs in the digestive tract. These organisms can enter through mouth,
usually with contaminated food and beverages. Treatment of diseases caused by
Salmonella typhi bacteria usually uses the Ciprofloxacin. The use of antibiotics can cause
side effects. The skin of M. paradisiaca L. is a type of plant that can be used as a natural
medicine. M. paradisiaca L. peel contains alkoloid compounds, flavonoids, saponins,
tannins and which can inhibit bacterial growth. The purpose of this study was to
determine the antibacterial activity of ethanol 96% extract of kepok banana peel (Musa
paradisiaca L.) waste.
This research included descriptive post test with control using maceration method
as an antibacterial activity test and was carried out at the Laboratory Bacteriology of
STIKES National from February - June 2019. The population in this study was kepok
banana peel (Musa paradisiaca L.). The sampling technique in this study used Quta
Sampling.
The concentration of M. paradisiaca L. peel extract used was 20%, 40%, 60%,
80% and 100%. Based on the results of the study it was found that the M. paradisiaca L.
peel inhibition zone on the growth of Salmonella typhi at a concentration of 20% was
6.03 mm, the concentration of 40% was 6.33 mm, the concentration of 60% was 6.78
mm, the concentration of 80% was 7, 33 mm and 100% concentration of 8.25% in the
resistance limit because the inhibition zone was less than 15 mm. The conclusion of this
study is that the ethanol extract 96% of M. paradisiaca L. peel is able to form a radical
has the ability to inhibit the growth of Salmonella typhi bacteria. The inhibition zone
produced by ethanol extract 96% of M. paradisiaca L. peel is smaller compared to
positive control, namely Ciprofloxacin 5 ?g with an average yield of 38.50 mm