UJI AKTIVITAS ANTIBAKTERI NANOPARTIKEL EKSTRAK ETANOL
BUNGA TELANG (Clitoria ternatea L) TERHADAP BAKTERI
Staphylococcus aureus dan Staphylococcus epidermidis YANG DIISOLASI
PADA JERAWAT
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Institusion
Sekolah Tinggi Ilmu Kesehatan Nasional
Author
Islely, Puspitarini
Subject
RN Pharmacy and Pharmaceutical Mathematics
Datestamp
2020-12-23 06:31:22
Abstract :
Acne is a skin disorder caused by excess oil gland production, due to hormonal or bacterial infection. Natural ingredients have far less side effects when compared to chemical drugs. One of the herbal ingredients that can be used as antibacterial is Telang flower (Clitoria ternatea L). The advantages contained in Telang flowers can be increased by turning them into nanoparticles. Purpose of this research is to determine whether the ethanol extract nanopartikel of telang flower have antibakterial activity against Staphylococcus aureus and Staphylococcus epidermidis. The thick extract of the Telang flower was obtained by maceration using 70% ethanol. The nanoparticles used chitosanNaTPP polymer using the ionic gelation method. Furthermore, the antibacterial activity was tested with the well method against Staphylococcus aureus and Staphylococcus epidermidis bacteria with the amount of Telang flower ethanol extract nanoparticles namely 17µg, 33µg, 49µg and 66µg and compared with 0.5% clindamycin (positive control) and nanoparticles without the addition of extract (negative control). Data were then analyzed with SPSS using One-way ANOVA. The results showed that the antibacterial activity test of nanoparticle extract of Telang flower at a amount of 17µg shows the largest inhibition zone of 16,23mm against Staphylococcus aureus bacteria and 26,37mm against Staphylococcus epidermidis bacteria. The result of the analysis using SPSS in the Post Hoc Test showed that there was not different in antibacterial acticity antibacterial against Staphylococcus aureus and Staphylococcus epidermidis bacterial at a amount 66µg ethanol of telang flower compered with positive controls
Acne is a skin disorder caused by excess oil gland production, due to hormonal or bacterial infection. Natural ingredients have far less side effects when compared to chemical drugs. One of the herbal ingredients that can be used as antibacterial is Telang flower (Clitoria ternatea L). The advantages contained in Telang flowers can be increased by turning them into nanoparticles. Purpose of this research is to determine whether the ethanol extract nanopartikel of telang flower have antibakterial activity against Staphylococcus aureus and Staphylococcus epidermidis. The thick extract of the Telang flower was obtained by maceration using 70% ethanol. The nanoparticles used chitosanNaTPP polymer using the ionic gelation method. Furthermore, the antibacterial activity was tested with the well method against Staphylococcus aureus and Staphylococcus epidermidis bacteria with the amount of Telang flower ethanol extract nanoparticles namely 17µg, 33µg, 49µg and 66µg and compared with 0.5% clindamycin (positive control) and nanoparticles without the addition of extract (negative control). Data were then analyzed with SPSS using One-way ANOVA. The results showed that the antibacterial activity test of nanoparticle extract of Telang flower at a amount of 17µg shows the largest inhibition zone of 16,23mm against Staphylococcus aureus bacteria and 26,37mm against Staphylococcus epidermidis bacteria. The result of the analysis using SPSS in the Post Hoc Test showed that there was not different in antibacterial acticity antibacterial against Staphylococcus aureus and Staphylococcus epidermidis bacterial at a amount 66µg ethanol of telang flower compered with positive controls
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