Abstract :
Diabetes mellitus is a degenerative disease that suffers quite a lot of people
in Indonesia, which is the 7th most ranked country in the world in 2015 according
to the IDF (International Diabetes Federation). Drug interaction is a reaction that
can occur if two or more medicinal ingredients meet in the human body and can
harm patients and harm the patient?scondition because it can cause toxicity. This
research was conducted descriptively with literature and retrospective data
collection in January to June 2018. The study was conducted on 14 type 2 DM
patients at Sangkrah health center. The results of the study showed that there was
a large potential for drug intractions with a percentage of 74,30%. The percentage
based on the mechanism include the pharmacodynamic mechanism of 65,85%,
pharmacokinetic interactions of 26,83%.