Institusion
Sekolah Tinggi Ilmu Kesehatan Nasional
Author
Arditya, Purwa Firgantara
Subject
RN Pharmacy and Pharmaceutical Mathematics
Datestamp
2021-03-02 03:50:55
Abstract :
Sawo Kecik (Manilkara kauki) is a plant in the from of a tree that can
reach a height of 30 meters and a trunk diameter of more than 100 cm, thick stem
buttress with a height of 1,5 meters, has mature leaves marked with dark green.
Sawo Kecik (Manilkara kauki) brown spreading in Indonesia, the area of
distribution is northern Sumatra, Java, Madura, Bali, Sulawesi, Maluku, and
Sumbawa. Sawo Kecik (Manilkara kauki) has a variety of compounds including
flavonoids, saponins, alkaloids, and tannins. The purpose of using the Sawo Kecik
(Manilkara kauki) leaf part is to out the leaves are able to inhibit the growth of
antibacterial with 96% ethanol extract against Klebsiella pneumoniae, the method
used is Kirby Bauer with positive control Ciprofloxacin, negative control DMSO.
The result showed that extract of sapodilla leaves can inhibit bacterial growth with
inhibitory zone at a concentration of 100% by 17,60 mm, a concentration of a
75% by 16,50 mm, a concentration of 50% by 15,70 mm and a concentration of a
25% by 13,90 mm.