UJI DAYA HAMBAT ANTIBAKTERI EKSTRAK ETANOL
96% DAUN KENIKIR (Cosmos caudatus Kunth) TERHADAP
Klebsiella pneumoniae
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Institusion
Sekolah Tinggi Ilmu Kesehatan Nasional
Author
Rian, Budi Utomo
Subject
RN Pharmacy and Pharmaceutical Mathematics
Datestamp
2021-03-02 03:54:46
Abstract :
Klebsiella pneumonia is a bacterium that can cause disease such as respiratory infections, urinary tract infections and liver abscesses. Kenikir leaves (Cosmos caudatus Kunth) can be used as antibacterial. Kenikir leaves (Cosmos caudatus Kunth) countain Flavonoids, alkaloids, tannins, saponins, and essential oils. The purpose of this study to determine the antibacterial inhibition test of the ethanol extract of kenikir leaves (Cosmos caudatus Kunth) on the growth of the bacterium Klebsiella pneumoniae and the most potencial concentration to inhibit the growth of Klebsiella pneumoniae. The method used is the disc diffusion (Kirby & Bauer) with a series of concentrations of 25%, 50%, 75% and 100%. The results of inhibition zone were analyzed using Mc Excel. The results demonstrated inhibition zone of the extract at a concentration of 25%, 50%, 75%, 100% of the ethanol extract of kenikir leaves (Cosmos caudatus Kunth) are 9,9 mm; 12,1 mm; 14,1 mm; and 17,0 mm. The highest ability of ethanol extract of kenikir leaves inhibition at 100% concentration, and the antibiotic ciprofloxacin has a diameter of 27,7 mm zone of inhibition
Klebsiella pneumonia is a bacterium that can cause disease such as respiratory infections, urinary tract infections and liver abscesses. Kenikir leaves (Cosmos caudatus Kunth) can be used as antibacterial. Kenikir leaves (Cosmos caudatus Kunth) countain Flavonoids, alkaloids, tannins, saponins, and essential oils. The purpose of this study to determine the antibacterial inhibition test of the ethanol extract of kenikir leaves (Cosmos caudatus Kunth) on the growth of the bacterium Klebsiella pneumoniae and the most potencial concentration to inhibit the growth of Klebsiella pneumoniae. The method used is the disc diffusion (Kirby & Bauer) with a series of concentrations of 25%, 50%, 75% and 100%. The results of inhibition zone were analyzed using Mc Excel. The results demonstrated inhibition zone of the extract at a concentration of 25%, 50%, 75%, 100% of the ethanol extract of kenikir leaves (Cosmos caudatus Kunth) are 9,9 mm; 12,1 mm; 14,1 mm; and 17,0 mm. The highest ability of ethanol extract of kenikir leaves inhibition at 100% concentration, and the antibiotic ciprofloxacin has a diameter of 27,7 mm zone of inhibition
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