GAMBARAN PENURUNAN FUNGSI HATI PADA PASIEN
DENGAN PENGOBATAN OBAT ANTI TUBERKULOSIS
(OAT) DI RUMAH SAKIT PANTI WALUYO SURAKARTA
PERIODE TAHUN 2019
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Institusion
Sekolah Tinggi Ilmu Kesehatan Nasional
Author
Sri, Kusrini
Subject
RN Pharmacy and Pharmaceutical Mathematics
Datestamp
2021-03-02 03:55:50
Abstract :
Tuberculosis (TB) is a contagious infectious disease caused by Mycobacterium tuberculosis. Indonesia ranks second with TB incidence below India. AntiTuberculosis Drug Therapy (OAT) given is inseparable from side effects, one of which is hepatotoxicity (decreased liver function). Laboratory tests of transaminase enzymes including SGOT and SGPT will show hepatotoxicity/decreased liver function. To determine the characteristics of patients receiving OAT therapy based on sex, age, and decreased liver function. This research is a non-experimental descriptive study. The study sample consisted of 57 patients with OAT treatment. TB most occurred in men as many as 33 patients (58%) and the highest age range suffering from TB was 36-45 years as many as 30 patients (52.63%) and patients who experienced a decrease in liver function by 4 patients (7 , 02%), while 14.03% experienced an increase in SGOT and SGPT <3 times ULN, and 78.95% had an increase in SGOT and SGPT that were still within normal limits.
Tuberculosis (TB) is a contagious infectious disease caused by Mycobacterium tuberculosis. Indonesia ranks second with TB incidence below India. AntiTuberculosis Drug Therapy (OAT) given is inseparable from side effects, one of which is hepatotoxicity (decreased liver function). Laboratory tests of transaminase enzymes including SGOT and SGPT will show hepatotoxicity/decreased liver function. To determine the characteristics of patients receiving OAT therapy based on sex, age, and decreased liver function. This research is a non-experimental descriptive study. The study sample consisted of 57 patients with OAT treatment. TB most occurred in men as many as 33 patients (58%) and the highest age range suffering from TB was 36-45 years as many as 30 patients (52.63%) and patients who experienced a decrease in liver function by 4 patients (7 , 02%), while 14.03% experienced an increase in SGOT and SGPT <3 times ULN, and 78.95% had an increase in SGOT and SGPT that were still within normal limits.
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