Abstract :
Cigarette smoke contains harmful substances. Prolonged exposure to
cigarette smoke causes a chronic inflammatory reaction. Exposure to cigarette
smoke damages the endothelium due to the presence of free radicals such as
nitrogen monoxide and hydrogen peroxide. These free radicals cause oxidative
stress. This oxidative stress causes a systemic acute phase reaction resulting in
inflammation as well as an increase in fibrinogen, blood cell count, blood viscosity
and the formation of rouleaux. The purpose of this study was to describe the value
of the erythrocyte sedimentation rate in tobacco smokers at the Mardi Lestari
General Hospital, Sragen.
The type of research used is observational descriptive research. This
research was conducted at the Mardi Lestari General Hospital Laboratory, Sragen.
This research was conducted on July 6, 2021. The sample in this study were
employees of tobacco smokers at the Mardi Lestari General Hospital, Sragen with
a total of 17. The sample of this study used a total sampling technique. The variable
in this study is the value of the erythrocyte sedimentation rate using the Westergren
method with units of mm/hour.
Based on this research, it is known that from 17 respondents, 5
respondents have high LED values and 12 respondents have normal LED values.
The average value of the LED values in 17 respondents was 14.35 mm/hour with a
range of values from 5-39 mm/hour.
The conclusion of this study is that some of the smokers who are more
than 5 years old, use non-filtered cigarettes and are included in the heavy smoker
category, have high LED values.