KESESUAIAN PENGGUNAAN OBAT PASIEN
SIROSIS HEPATIS DI RUMAH SAKIT
ISLAM AMAL SEHAT SRAGEN
PERIODE TAHUN 2017–2019
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Institusion
Sekolah Tinggi Ilmu Kesehatan Nasional
Author
Upik, Indriyani
Subject
RN Pharmacy and Pharmaceutical Mathematics
Datestamp
2020-12-23 02:27:01
Abstract :
Hepatic cirrhosis is the end result of hepatocyte damage characterized by damage to the normal structure of the liver due to the formation of connective tissue and nodules. Complications of cirrhosis are portal hypertension, varicose veins in the gastrointestinal tract: esophageal varices, ascites, liver encephalopathy and blood clotting disorders (coagulopathy). WHO data (2004), the world prevalence of liver cirrhosis is 1.3% and ranks eighteen causes of death. This study aims to determine the patient's characteristics and suitability in drug use based on the types of complications suffered by hepatic cirrhosis patients at RS Islam Amal Sehat Sragen. The method used is a descriptive non-experimental study with a sample of 80 patients and retrospectively with saturated sampling technique. The results of this study indicate that the characteristics of the most patients suffering from liver cirrhosis are male gender 78.75%, according to age most at age 56-65 years 33,75% and type the highest complication was acites of 36,25%. In this study the suitability of drug use in the management of hepatic cirrhosis complications in accordance with Pharmacoterhapy Handbook Ninth Edition is for esophageal varices 100%, SBP 92,86%, acites 58,62% and hepatic ensefalopathy 33,33%.
Hepatic cirrhosis is the end result of hepatocyte damage characterized by damage to the normal structure of the liver due to the formation of connective tissue and nodules. Complications of cirrhosis are portal hypertension, varicose veins in the gastrointestinal tract: esophageal varices, ascites, liver encephalopathy and blood clotting disorders (coagulopathy). WHO data (2004), the world prevalence of liver cirrhosis is 1.3% and ranks eighteen causes of death. This study aims to determine the patient's characteristics and suitability in drug use based on the types of complications suffered by hepatic cirrhosis patients at RS Islam Amal Sehat Sragen. The method used is a descriptive non-experimental study with a sample of 80 patients and retrospectively with saturated sampling technique. The results of this study indicate that the characteristics of the most patients suffering from liver cirrhosis are male gender 78.75%, according to age most at age 56-65 years 33,75% and type the highest complication was acites of 36,25%. In this study the suitability of drug use in the management of hepatic cirrhosis complications in accordance with Pharmacoterhapy Handbook Ninth Edition is for esophageal varices 100%, SBP 92,86%, acites 58,62% and hepatic ensefalopathy 33,33%.
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