Institusion
Sekolah Tinggi Ilmu Kesehatan Nasional
Author
Priskilla, Rachma Widya Putri
Subject
RN Pharmacy and Pharmaceutical Mathematics
Datestamp
2020-12-23 02:27:34
Abstract :
Medical studies have shown that free radicals are involved in a variety of
pathological processes. Most of the diseases begin with an excessive oxidation
reaction in the body. The reactivity of free radicals can be inhibited by antioxidant
systems. Antioxidants is an inhibitor used to inhibit autooxidation by scavenge
free radicals and highly reactive molecules than damage cells will be inhibited.
Plants that can be used as an compound antiradical is garlic and the leaves of
marigolds have a flavonoid compounds that can be used as antioxidant.
This study was conducted to determine antiradical DPPH (1,1 diphenyl-2-
Picrilhidrazyl) activity of the combination of garlic extract and extract of leaves
of marigolds in compotition 0: 1, 1: 0, 1: 2, and 2: 1. The methode extraction is
done by maceration with 96% ethanol. The resultsof antiradical DPPH activity
test showed that the combination has better than singular. The value of IC50
combination 1: 0 0: 1 1: 2 and 2: 1 are 101.7396 ppm, 47.4365 ppm, 34.5455
ppm, 42.1154 ppm, respectively.