UJI TOKSISITAS AKUT FRAKSI N-HEKSAN BAWANG
LANANG HITAM (Allium sativum L.) PADA MENCIT PUTIH
JANTAN
Total View This Week0
Total View This Week0
Institusion
Sekolah Tinggi Ilmu Kesehatan Nasional
Author
Nurul, Adi Aryani
Subject
RN Pharmacy and Pharmaceutical Mathematics
Datestamp
2022-07-05 02:09:15
Abstract :
Black garlic is a plant that is widely used as traditional medicine so it is necessary to know the level of safety. The study was conducted experimentally with the aim of knowing the LD50 value and toxic symptoms of the administration of the n-hexane fraction of black garlic to male white mice with acute toxicity test. Observations were carried out intensively for 30 minutes, the first 4 hours after treatment and continued 24 hours after treatment with oral doses of the n-hexane fraction of black garlic cloves 2,38 mg/20g BW, 2,97 mg/20g BW and 3,57 mg/20g BW. Toxic symptoms observed included changes in body weight, behavior, changes in color and hair loss, and feces. Observations showed that the n-hexane fraction of black onion did not cause toxic effects or was included in the practically non-toxic category in test animals as evidenced by the absence of death in test animals after 24 hours of treatment.
Black garlic is a plant that is widely used as traditional medicine so it is necessary to know the level of safety. The study was conducted experimentally with the aim of knowing the LD50 value and toxic symptoms of the administration of the n-hexane fraction of black garlic to male white mice with acute toxicity test. Observations were carried out intensively for 30 minutes, the first 4 hours after treatment and continued 24 hours after treatment with oral doses of the n-hexane fraction of black garlic cloves 2,38 mg/20g BW, 2,97 mg/20g BW and 3,57 mg/20g BW. Toxic symptoms observed included changes in body weight, behavior, changes in color and hair loss, and feces. Observations showed that the n-hexane fraction of black onion did not cause toxic effects or was included in the practically non-toxic category in test animals as evidenced by the absence of death in test animals after 24 hours of treatment.
Download
book
BibTex
Latex, Jabref
cloud_download
Original Resource
url resource Institution
