KESESUAIAN PROSES REKONSTITUSI ANTIBIOTIK
INJEKSI DI BANGSAL ANAK RUMAH SAKIT
UMUM ASSALAM GEMOLONG SRAGEN
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Institusion
Sekolah Tinggi Ilmu Kesehatan Nasional
Author
Mustika, Anggrahini
Subject
RN Pharmacy and Pharmaceutical Mathematics
Datestamp
2022-07-05 02:09:26
Abstract :
Reconstitution is a process of combining solvent or carrier medium into dry powder mass to produce suspended or dissolved substance conducted aseptically. This research aims to find out the compatibility of dry powder injection antibiotic reconstituting process in child unit of Assalam Gemolong Public Hospital, Sragen. This study was a descriptive research by collecting data through direct observation using checklist for 1 (one) month, December 2021-January 2022. This research was conducted using total sampling obtaining 99 reconstitution actions being the sample. The result of research shows the percentage compatibility of injection antibiotic reconstitution process based on SPO and Guidelines of Drug Mixing in Assalam Gemolong Public Hospital Sragen, including the compatibility of dosage calculation, appropriate solvent choice, and appropriate storage following reconstitution (100%), the compatibility of solvent volume used (62.63%), compatibility of drug labelling (76.77%), the compatibility of drug mixing aseptically (58.58%), and the compatibility of disposal method in which all used drugs combinations are put into specific wrap (88.89%). Meanwhile, based on Pediatric Injectable Drug 10th edition and Handbook on Injectable Drugs 17th edition, it can be found the compatible dosing (90.91%), the compatible solvent choice and the compatible storage following reconstitution (100%), and the compatible solvent volume used (58.59%). Conclusion: the percentage compatibility of injection antibiotic reconstitution process based on SPO and guidelines of Drug Mixing in RSU Assalam Gemolong Sragen is 83.84% from 7 aspects of observation. Meanwhile, the percentage based on Pediatric Injectable Drug 10th edition and Handbook on Injectable Drugs 17th edition is 87.37% from 4 aspects of observation
Reconstitution is a process of combining solvent or carrier medium into dry powder mass to produce suspended or dissolved substance conducted aseptically. This research aims to find out the compatibility of dry powder injection antibiotic reconstituting process in child unit of Assalam Gemolong Public Hospital, Sragen. This study was a descriptive research by collecting data through direct observation using checklist for 1 (one) month, December 2021-January 2022. This research was conducted using total sampling obtaining 99 reconstitution actions being the sample. The result of research shows the percentage compatibility of injection antibiotic reconstitution process based on SPO and Guidelines of Drug Mixing in Assalam Gemolong Public Hospital Sragen, including the compatibility of dosage calculation, appropriate solvent choice, and appropriate storage following reconstitution (100%), the compatibility of solvent volume used (62.63%), compatibility of drug labelling (76.77%), the compatibility of drug mixing aseptically (58.58%), and the compatibility of disposal method in which all used drugs combinations are put into specific wrap (88.89%). Meanwhile, based on Pediatric Injectable Drug 10th edition and Handbook on Injectable Drugs 17th edition, it can be found the compatible dosing (90.91%), the compatible solvent choice and the compatible storage following reconstitution (100%), and the compatible solvent volume used (58.59%). Conclusion: the percentage compatibility of injection antibiotic reconstitution process based on SPO and guidelines of Drug Mixing in RSU Assalam Gemolong Sragen is 83.84% from 7 aspects of observation. Meanwhile, the percentage based on Pediatric Injectable Drug 10th edition and Handbook on Injectable Drugs 17th edition is 87.37% from 4 aspects of observation
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