Abstract :
Antibacterial and antioxidant test have been conducted using methanol extract of leave and
stem bark of Artocarpus for its application as peel-off mask. The raw material was macerated
using methanol and the obtained filtrate was evaporated until the concentrated crude extract
was obtained. The crude extract is tested using several tests, such a phytochemistry
screening, antibacterial test to Propionibakterium acnes and Staphylococcus aureus with the
concentration of extract of 50; 100; 150 and 200 ppm, and antioxidant test using DPPH
method. The additional test was conducted for evaluating the characteristic of peel-off mask,
such as homogeneity, pH, organoleptic and irritation test. The result of photochemistry
screening showed those extracts were dominated with tannin and saponin. The antibacterial
test to P. acnes showed the leave extract with concentration of 50, 100, 150 and 200 ppm
showed the inhibition zone 9,6; 9,9; 10,4 and 11,3 mm. The other extract, the stem bark
extract, provided the inhibition zone 8,4; 8,8; 9,5 and 10,5 mm at the similar concentraion of
extract. For Staphyliococcus aureus, the leaves extract showed the inhibition zone 7,5; 7,8;
8,2 and 8,8 mm, while the stem bark extract 6,2; 6,4; 7,7 dan 9,2 mm. Those result revealed
that the leave extract is more powerful to inhibit P. acnes than stem bark extract. But the
different result was obtained when discussed about the inhibition of S. aureus, the stem bark
extract showed the higher activity than leave extract. The measurement of antioxidant of
leave extract at concentration 50; 100; 150 and 200 ppm showed the following activity data
22,91; 31,90; 32,76 and 40,47%, then the stem bark extract has the followong activity data
43,89; 64,66; 70,02; 70,44%. These data showed the antioxidant activity of stem bark extract
is higher than stem bark extract. The clinical testing of peel-off mask formulation showed
that the FDN1, FDN2 and FDN3 has a good homogeneity and the pH was 6,7; 6,7 and 5,8.
The irritation test showed a negative reasult for all of formulation.