STUDI LITERATUR : KANDUNGAN SENYAWA KIMIA DAN AKTIVITAS FARMAKOLOGI MINYAK ZAITUN EKSTRA MURNI (EXTRA VIRGIN OLIVE OIL)
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Institusion
Universitas Muslim Indonesia
Author
Sulastri, Riska
Azizah, Rizqi Nur
Handayani, Selpida
Azizah, Rizqi Nur
Handayani, Selpida
Subject
RS Pharmacy and materia medica
Datestamp
2024-05-27 02:10:06
Abstract :
RISKA SULASTRI. Studi literatur : kandungan senyawa kimia dan aktivitas farmakologi minyak zaitun ekstra murni (ekstra virgin olive oil). (Dibimbing oleh Rizqi Nur Azizah dan Selpida Handayani). Extra Virgin Olive Oil (EVOO) termasuk bahan makanan fungsional yang mengandung zat gizi, senyawa makronutrien dan mikronutrien yang memberikan efek fisiologis spesifik untuk kesehatan. Otoritas Keamanan Pangan Eropa (EFSA) telah menyetujui pada tahun 2011 klaim kesehatan yang menyatakan bahwa asupan makanan dari EVOO yang mengandung senyawa polifenol mampu melindungi lipid darah dari kerusakan oksidatif. Penelitian ini bertujuan untuk mengetahui kandungan senyawa kimia yang terdapat dalam Extra Virgin Olive Oil (EVOO) dan bagaimana aktivitas farmakologi yang ditimbulkan. Penelitian ini dilakukan dengan menggunakan metode narative review. Berdasarkan pencarian yang telah dilakukan diperoleh sebanyak 7 jurnal yang dikaji kemudian didapatkan hasil yaitu kandungan senyawa kimia yang terdapat di dalam EVOO adalah Fenol, Hydroxytyrosol, Tyrosol, Elenolic acid derivatives, Elenolic acid, Oleacin, Oleocanthal, Oleuropein aglycone, Secoiridoids derivatives dan Lignans. Senyawa tersebut memiliki aktivitas sebagai antiinflamasi, antipoliferasi, dan antioksidan yang mampu memberikan efek farmakolgi dalam pengobatan dan pencegahan berbagai jenis penyakit diantaranya, penyakit ginjal kronik, penyakit alzeimer, lupus eritematosus sistemik, dismenore primer (hiperkontraksi uterus) dan Kanker hati. Kata Kunci : Extra virgin olive oil (EVOO). Minyak zaitun ekstra murni, Pharmacology, Bioactive Compound. ABSTRACT RISK SULASTRI. Literature study: chemical compound content and pharmacological activity of extra virgin olive oil. (Supervised by Rizqi Nur Azizah and Selpida Handayani). Extra Virgin Olive Oil (EVOO) is a functional food ingredient that contains nutrients, macronutrient and micronutrient compounds that provide specific physiological effects for health. The European Food Safety Authority (EFSA) has approved in 2011 a health claim stating that dietary intake of EVOO containing polyphenolic compounds is able to protect blood lipids from oxidative damage. This research aims to determine the chemical compounds contained in Extra Virgin Olive Oil (EVOO) and the pharmacological activity they cause. This research was conducted using the narrative review method. Based on the search that had been carried out, a total of 7 journals were reviewed and the results obtained were that the chemical compounds contained in EVOO were Fenol, Hydroxytyrosol, Tyrosol, Elenolic acid derivatives, Elenolic acid, Oleacin, Oleocanthal, Oleuropein aglycone, Secoiridoids derivatives and Lignans. This compound has anti-inflammatory, anti-proliferative and antioxidant activity which is capable of providing pharmacological effects in the treatment and prevention of various types of diseases including chronic kidney disease, Alzheimer's disease, systemic lupus erythematosus, primary dysmenorrhea (uterine hypercontraction) and liver cancer. Keywords: Extra virgin olive oil (EVOO). Extra virgin olive oil, Pharmacology, Bioactive Compound.
RISKA SULASTRI. Studi literatur : kandungan senyawa kimia dan aktivitas farmakologi minyak zaitun ekstra murni (ekstra virgin olive oil). (Dibimbing oleh Rizqi Nur Azizah dan Selpida Handayani). Extra Virgin Olive Oil (EVOO) termasuk bahan makanan fungsional yang mengandung zat gizi, senyawa makronutrien dan mikronutrien yang memberikan efek fisiologis spesifik untuk kesehatan. Otoritas Keamanan Pangan Eropa (EFSA) telah menyetujui pada tahun 2011 klaim kesehatan yang menyatakan bahwa asupan makanan dari EVOO yang mengandung senyawa polifenol mampu melindungi lipid darah dari kerusakan oksidatif. Penelitian ini bertujuan untuk mengetahui kandungan senyawa kimia yang terdapat dalam Extra Virgin Olive Oil (EVOO) dan bagaimana aktivitas farmakologi yang ditimbulkan. Penelitian ini dilakukan dengan menggunakan metode narative review. Berdasarkan pencarian yang telah dilakukan diperoleh sebanyak 7 jurnal yang dikaji kemudian didapatkan hasil yaitu kandungan senyawa kimia yang terdapat di dalam EVOO adalah Fenol, Hydroxytyrosol, Tyrosol, Elenolic acid derivatives, Elenolic acid, Oleacin, Oleocanthal, Oleuropein aglycone, Secoiridoids derivatives dan Lignans. Senyawa tersebut memiliki aktivitas sebagai antiinflamasi, antipoliferasi, dan antioksidan yang mampu memberikan efek farmakolgi dalam pengobatan dan pencegahan berbagai jenis penyakit diantaranya, penyakit ginjal kronik, penyakit alzeimer, lupus eritematosus sistemik, dismenore primer (hiperkontraksi uterus) dan Kanker hati. Kata Kunci : Extra virgin olive oil (EVOO). Minyak zaitun ekstra murni, Pharmacology, Bioactive Compound. ABSTRACT RISK SULASTRI. Literature study: chemical compound content and pharmacological activity of extra virgin olive oil. (Supervised by Rizqi Nur Azizah and Selpida Handayani). Extra Virgin Olive Oil (EVOO) is a functional food ingredient that contains nutrients, macronutrient and micronutrient compounds that provide specific physiological effects for health. The European Food Safety Authority (EFSA) has approved in 2011 a health claim stating that dietary intake of EVOO containing polyphenolic compounds is able to protect blood lipids from oxidative damage. This research aims to determine the chemical compounds contained in Extra Virgin Olive Oil (EVOO) and the pharmacological activity they cause. This research was conducted using the narrative review method. Based on the search that had been carried out, a total of 7 journals were reviewed and the results obtained were that the chemical compounds contained in EVOO were Fenol, Hydroxytyrosol, Tyrosol, Elenolic acid derivatives, Elenolic acid, Oleacin, Oleocanthal, Oleuropein aglycone, Secoiridoids derivatives and Lignans. This compound has anti-inflammatory, anti-proliferative and antioxidant activity which is capable of providing pharmacological effects in the treatment and prevention of various types of diseases including chronic kidney disease, Alzheimer's disease, systemic lupus erythematosus, primary dysmenorrhea (uterine hypercontraction) and liver cancer. Keywords: Extra virgin olive oil (EVOO). Extra virgin olive oil, Pharmacology, Bioactive Compound.
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