Standardisasi Simplisia Dan Ektrak Etanol 70% Kulit Buah Manggis (Garcinia Mangostana L.)
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Institusion
Universitas Airlangga
Author
Alif Noviana Ismi
Subject
R Medicine
Datestamp
2020-12-15 23:33:03
Abstract :
Mangosteen (Garcinia mangostana L.)?s rind will be developed as herbal drug. So, it should be standardized with determine standard parameters based on Herbal Pharmacopeia of Indonesia. It contains xanthone as secondary metabolite and ?-mangosteen as primary metabolite that useful for anti-diabetic (Yousif et al., 2016). The result of the standard parameter of mangosteen rind simplicial showed determination of : organoleptic was dark brown, non-aromatic smell, and bitter taste; loss of drying was (9,28 + 0,10) %; ash content was (3,22 + 0,07) %; ash content insoluble in acidic was (0,56 + 0,05) %; dissolved compound in water was (6,91 + 0,41) %; dissolved compound in ethanol was (11,75 + 0,54) %; chromatographic profile by TLC showed that mangosteen rind contain ?-mangosteen. TLC- Densitometric method was used for determination of ?-mangosteen in mangosteen rind and it contained (18,03 + 0,79) % b/b of ?-mangosteen. And the result of the standard parameter of mangosteen rind 70% ethanol extract showed determination of : organoleptic was dark brown, non-aromatic smell, and bitter taste; water loss content was (9,28 + 0,10) %; ash content was (3,22 + 0,07) %; ash content insoluble in acidic was (0,56 + 0,05) %; dissolved compound in water was (6,91 + 0,41) %; dissolved compound in ethanol was (11,75 + 0,54) %; chromatographic profile by TLC showed that mangosteen rind contain ?-mangosteen. TLC- Densitometric method was used for determination of ?-mangosteen in mangosteen rind and it contained (33,49 + 0,81) % b/b of ?-mangosteen. It is concluded that both of them have qualified by the standard requirements based on Herbal Pharmacopeia of Indonesia.
Mangosteen (Garcinia mangostana L.)?s rind will be developed as herbal drug. So, it should be standardized with determine standard parameters based on Herbal Pharmacopeia of Indonesia. It contains xanthone as secondary metabolite and ?-mangosteen as primary metabolite that useful for anti-diabetic (Yousif et al., 2016). The result of the standard parameter of mangosteen rind simplicial showed determination of : organoleptic was dark brown, non-aromatic smell, and bitter taste; loss of drying was (9,28 + 0,10) %; ash content was (3,22 + 0,07) %; ash content insoluble in acidic was (0,56 + 0,05) %; dissolved compound in water was (6,91 + 0,41) %; dissolved compound in ethanol was (11,75 + 0,54) %; chromatographic profile by TLC showed that mangosteen rind contain ?-mangosteen. TLC- Densitometric method was used for determination of ?-mangosteen in mangosteen rind and it contained (18,03 + 0,79) % b/b of ?-mangosteen. And the result of the standard parameter of mangosteen rind 70% ethanol extract showed determination of : organoleptic was dark brown, non-aromatic smell, and bitter taste; water loss content was (9,28 + 0,10) %; ash content was (3,22 + 0,07) %; ash content insoluble in acidic was (0,56 + 0,05) %; dissolved compound in water was (6,91 + 0,41) %; dissolved compound in ethanol was (11,75 + 0,54) %; chromatographic profile by TLC showed that mangosteen rind contain ?-mangosteen. TLC- Densitometric method was used for determination of ?-mangosteen in mangosteen rind and it contained (33,49 + 0,81) % b/b of ?-mangosteen. It is concluded that both of them have qualified by the standard requirements based on Herbal Pharmacopeia of Indonesia.
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