Abstract :
Background - Fentanyl is the drug often used to control post operative pain, there has been a
tendency to switch to oxycodone. Oxycodone has been included in the national formulary
(FORNAS) since 2018. In addition, many studies have shown the analgesic effect of oxycodone
is better than fentanyl for postoperative pain management.
Objective - To analyze the cost-effectiveness of fentanil and oxycodone in postoperative pain
patients
Methods - A RCT single blind, two group study of 20 patients post operative divided into 2
groups. The first group (n = 10 patients) treated with fentanil and the other group (n = 10
patients) treated with oxycodone. Observations carried out for twelve hours. The efficacy of
therapy was measured by NRS pain scale.
Results and Conclusion - The NRS pain scale after 12 hours showed no difference both two
group, so it could be said that both fentanyl and oxycodone had the same effectiveness in
reducing the NRS pain scale. In terms of cost fentanyl and oxycodone, the cost of oxycodone is
lower (Rp. 2.208.704) compared in the fentanyl group (Rp. 2.332.000). The ACER value in the
two groups showed no significant difference. The oxycodone group is more cost-effectiveness
than the fentanyl group with equal effectivity in post operative pain.