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Tingkat kesembuhan luka terbuka pada tikus putih (Rattus norvegicus) yang diberi salep daun kirinyuh (chromolaena odorata L)
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Institusion
Universitas Wijaya Kusuma Surabaya
Author
Posut, Moan Anjelus
Subject
Z665 Library Science. Information Science 
Datestamp
2021-09-28 08:19:33 
Abstract :
TINGKAT KESEMBUHAN LUKA TERBUKA PADA TIKUS PUTIH (Rattus norvegicus) YANG DIBERI SALEP DAUN KIRINYUH (chromolaena odorata) Anjelus Moan posut ABSTRACT The purpose of this study was to determine the rate of open wound healing based on the size of the wound diameter shrinkage in white rats (Rattus norvegicus) given the ointment of kirinyuh leaf extract (Chromolaena odorata) and to determine the appropriate concentration of kirinyuh leaf extract (Chromolaena Odorata) for healing open wounds in rats. white (Rattus norvegicus). This type of research is experimental with a completely randomized design (CRD). The sample used was 1 kg of kirinyuh leaves (Chromolaena odorata) obtained from Maumere NTT, 25 white rats (Rattus norvegicus) which were divided into 5 treatment groups and 5 replications. P0(-) is a negative control: 5 white rats (Rattus norvegicus) given aquadest. P4(+) is a positive control: 5 white rats (Rattus norvegicus) given bioplacenton ointment. P1 : 5 white rats (Rattus norvegicus) given 5% kirinyuh leaf extract ointment (Chromolaena odorata). P2 : 5 white rats (Rattus norvegicus) given 10% kirinyuh leaf extract ointment (Chromolaena odorata). P3 : 5 white rats (Rattus norvegicus) given 15% kirinyuh leaf extract ointment. The results showed a very significant difference between groups (P2) compared to groups (P1, P3, P4 and P0) (P<0.01). Based on the results of the study, it can be concluded that the leaf extract of kirinyuh (Chromolaena odorata) can be used as a ointment against white rats (Rattus norvegicus). Keywords: kirinyuh leaf ointment, open wound, Chromolaena odorata., Rattus norvegicus 
Institution Info

Universitas Wijaya Kusuma Surabaya