Abstract :
The prevalence of diabetes mellitus is increasing annually, especially type
2 diabetes. The costs spent on dm therapy reached usd 465 billion in 2011, and it
could be estimated that by 2030 it will increase by $595 billion. The purpose of
this study was to synthesize information on the cost effectiveness of treatment in
dm type 2 patients who use single oral antidiabetes drugs and a combination of
acer and icer values using a systematic literature review.
This research is a systematic literature review. Literature search was
performed using the keyword cost effectiveness of diabetes type 2 using the
Google Scholar journal search engine, PubMed, and Portal Garuda. The search
results were obtained as many as 344 articles and after filtering, 3 articles that met
the inclusion criteria were obtained. Most of the research designs used cross
sectional design. Articles that met inclusion criteria were subjected to a critical
appraisal.
The results of this study found that the highest cost effective use of single
oral antidiabetic is the sulfonylurea group with an ACER value of 128,900 and an
ICER value of -4,857, while the most cost effective use of combined oral
antidiabetic is the combination of the biguanide class and the sulfonylurea with an
ACER value of 2,215,351. and the ICER value is -170.208.