EFEK PEMBERIAN SEDUHAN TEH HITAM (Camellia sinensis L)
DAN COKELAT (Theobroma cacao L) TERHADAP GAMBARAN
HISTOPATOLOGIS HEPAR TIKUS PUTIH (Rattus norvegicus)
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Institusion
Sekolah Tinggi Ilmu Kesehatan Nasional
Author
Ema, Rochayani Damairia
Subject
R Medicine (General)
Datestamp
2022-04-14 07:38:57
Abstract :
Black tea is a member of the Theaceae family which has many benefits and contains higher caffeine than green tea. Chocolate is a commodity that generates foreign exchange for the country and is the main ingredient for making chocolate which also contains caffeine. Caffeine damages the liver by inhibiting the growth of connective tissue in liver cells. The purpose of this study was to determine the histopathological effect on the liver organs of white rats given black and chocolate tea steeping and the damage that occurs when given in a predetermined dose and time. This research is experimental, with 7 treatment groups. Liver organs were observed macroscopically and microscopically. The results of macroscopic observations there were no differences in the control and treatment groups. The results of microscopic observations in the black tea steeping group 3 and 6 mg/200 g/day, and chocolate steeping 3, 6, and 12 mg/200 g/day there was degeneration, black tea steeped 12 mg/200 g/day there was necrosis. The results of the Mann Whitney test showed a significant difference in the black tea steeping group at the three doses and 12 mg/200 gr/day chocolate steeping, while 3 and 6 mg/200gr/day chocolate steeping did not show a significant difference. It can be concluded that the administration of 3 and 6 mg/200 g/day steeping black tea and 3, 6, and 12 mg/200 g/day steeping black tea causes degeneration and 12 mg/200 g/day black tea steeping causes necrosis.
Black tea is a member of the Theaceae family which has many benefits and contains higher caffeine than green tea. Chocolate is a commodity that generates foreign exchange for the country and is the main ingredient for making chocolate which also contains caffeine. Caffeine damages the liver by inhibiting the growth of connective tissue in liver cells. The purpose of this study was to determine the histopathological effect on the liver organs of white rats given black and chocolate tea steeping and the damage that occurs when given in a predetermined dose and time. This research is experimental, with 7 treatment groups. Liver organs were observed macroscopically and microscopically. The results of macroscopic observations there were no differences in the control and treatment groups. The results of microscopic observations in the black tea steeping group 3 and 6 mg/200 g/day, and chocolate steeping 3, 6, and 12 mg/200 g/day there was degeneration, black tea steeped 12 mg/200 g/day there was necrosis. The results of the Mann Whitney test showed a significant difference in the black tea steeping group at the three doses and 12 mg/200 gr/day chocolate steeping, while 3 and 6 mg/200gr/day chocolate steeping did not show a significant difference. It can be concluded that the administration of 3 and 6 mg/200 g/day steeping black tea and 3, 6, and 12 mg/200 g/day steeping black tea causes degeneration and 12 mg/200 g/day black tea steeping causes necrosis.
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