POTENSI MINYAK ATSIRI BUNGA KENANGA (Cananga
odorata) SEBAGAI ANTI JERAWAT DALAM SEDIAAN
PATCH TRANSDERMAL
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Institusion
Sekolah Tinggi Ilmu Kesehatan Nasional
Author
Afifah, Rahadatul „Aisy
Subject
RN Pharmacy and Pharmaceutical Mathematics
Datestamp
2022-07-01 02:01:42
Abstract :
Ylang flower essential oil (Cananga odorata (Lmk).f.Thoms) has antibacterial activity which is used for the treatment of acne which is formulated into transdermal patch preparations because it can deliver drugs at a controlled speed to pass through the skin to produce a systemic effect. The preparation of this Transdermal Patch uses the solvent-casting method. This study aims to determine from the three formulas F1 (2.5ml), F2 (3ml) and F3 (4ml) ylang flower essential oil (Cananga odorata (Lmk).f.Thoms) which is effective in inhibiting Staphylococcus aureus bacteria which is one of the bacteria causing pimple. Ylang flower essential oil was obtained by steam distillation method and obtained 10 ml of oil and the yield was 0.2% v/w. The results showed that the formula that could inhibit the growth of Staphylococcus aureus bacteria was formula 3 with an inhibition zone diameter of 30.2 mm, a bacterial inhibition zone using a positive control of tetracycline and a negative control of aquades. The best formula for transdermal patch preparation of ylang flower essential oil as an anti-acne was shown in formula 3 with a concentration of 4 ml.
Ylang flower essential oil (Cananga odorata (Lmk).f.Thoms) has antibacterial activity which is used for the treatment of acne which is formulated into transdermal patch preparations because it can deliver drugs at a controlled speed to pass through the skin to produce a systemic effect. The preparation of this Transdermal Patch uses the solvent-casting method. This study aims to determine from the three formulas F1 (2.5ml), F2 (3ml) and F3 (4ml) ylang flower essential oil (Cananga odorata (Lmk).f.Thoms) which is effective in inhibiting Staphylococcus aureus bacteria which is one of the bacteria causing pimple. Ylang flower essential oil was obtained by steam distillation method and obtained 10 ml of oil and the yield was 0.2% v/w. The results showed that the formula that could inhibit the growth of Staphylococcus aureus bacteria was formula 3 with an inhibition zone diameter of 30.2 mm, a bacterial inhibition zone using a positive control of tetracycline and a negative control of aquades. The best formula for transdermal patch preparation of ylang flower essential oil as an anti-acne was shown in formula 3 with a concentration of 4 ml.
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