Abstract :
The process of reconstitution of sterile preparations must be considered in
terms of aseptic procedures, namely preparation, mixing, and storage techniques.
This study aims to describe the suitability of the application of aseptic dispensing
procedures for sterile injections of antibiotics in the Injectable Drug Mixing Unit
of RSUD Dr. Moewardi. The method used in this research is the descriptive
quantitative research method. Data analysis was carried out by calculating the
percentage of conformity of the application of aseptic dispensing procedures to
the Standard Operating Procedures for handling injection drug reconstitution and
the implementation of reconstitution in RSUD Dr. Moewardi, is said to be
appropriate if the percentage of conformity is >50% and not appropriate if <50%.
Data collection was carried out by direct observation of the act of mixing
antibiotic injections using a checklist sheet and interviews with officers at the
Injecting Drug Mixing Unit. Sampling was done by using a purposive sampling
technique. The results of the study obtained 172 actions of preparing and mixing
antibiotic injections, and 28 storing the rest of the reconstitution of antibiotic
injections. The results showed a picture of the suitability of the application of
aseptic dispensing procedures for sterile injections of antibiotics in the Injectable
Drug Mixing Unit of RSUD Dr. Moewardi at the preparation stage was 98.95%,
at the mixing stage it was 99.63%, and at the storage stage it was 82.14%. The
study concludes that the application of aseptic dispensing procedures for sterile
injections of antibiotics in the Injecting Drug Mixing Unit is by the Standard
Operating Procedures for handling injection drug reconstitution and the
implementation of reconstitution at RSUD Dr. Moewardi.