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Efek Pemberian Minyak Atsiri Kayu Manis (Cinnamomum Burmannii) Terhadap Gambaran Histopatologi Ginjal Tikus Putih Yang Diinduksi Streptozotocin
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Institusion
Universitas Airlangga
Author
Naomi Lan Noviana Thesia, -
Subject
SF600-1100 Veterinary medicine 
Datestamp
2021-10-14 23:18:45 
Abstract :
This study was conducted to investigate the antidiabetic effect of cinnamon essential oil (Cinnamomum burmannii) against STZ (streptozotocin). Single dose of STZ was intraperitoneally given 45 mg/kgBW. A total of twenty male rats were used in this study. Twenty male rats were used in this study. Those rats were divided into five groups: negative control group (K-) was not induced by streptozotocin and treated with 1% Tween 80; a positive control group (K+) induced by streptozotocin and treated with 1% Tween 80; treatment 1 (P1) induced by streptozotocin and gave cinnamon essential oil 100 mg/kgBW; treatment 2 (P2) induced by streptozotocin and gave cinnamon essential oil 200 mg/kgBW; treatment 3 (P3) induced by streptozotocin and gave cinnamon essential oil 400 mg/kgBW. The treatment was given daily for 14 days. Cinnamon essential oil is very potential to reduce degeneration of tubular cells, necrosis tubular, Glomerular necrosis and glomerulosclerosis. P3 treatment (400 mg/kgBW) of kidney shown minimal result. The conclusion is cinnamon essential oil can reduce the level of kidney cell damage, so that it can be developed as an antidiabetic herbal medicine. 
Institution Info

Universitas Airlangga